The E210 sells for the same price as the ML 1210 ($280 CAN). But the E210 toner cartridges sell for more than 1.5 times the price ($80 vs. $135 CAN). Not only that, the E210 cartridges are rated at only 2000 pages vs. 2500 for the Samsung.
So I felt I had nothing to lose, and didn't really think I would hurt the printer. I removed the tab and inserted an old Samsung cartridge (destroying a new cartridge would've been more heartbreaking than destroying the printer).
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On the other hand, the Lexmark filler is covered by a steel plate held in place by a screw with a tighen-only head. Apparently you can do some drilling to defeat this plate, but that's a more intrusive procedure than I'm prepared to undertake (at least while I have empty Samsung cartridges to play with).
I won't likely attempt a refill in the near future, but I'd be happy to hear from anybody who has.
I used Ebay to buy a pair of toner refill bottles. The price was US$ 11.00 for the pair, plus $8.75 shipping, handling & insurance. Total cost to me $US 19.75 ($CA 30.00). That's about 1/6 of the Samsung cartridge price and 1/10 of the Lexmark cartridge price.
I dumped one of the toner refills into the Samsung cartridge, reinstalled it in my Lexmark printer, and it worked fine. So my Ebay experience was a success.
Now I have my eye on the big toner refill bottles. Apparently there are a number of kinds of toner, and the manufacturers and rebuilders are very hush-hush about which toner goes in which machine. I believe I have inferred that the Samsung uses waste-free nonmagnetic micro-toner. Looks suspiciously the same as the toner for the photocopier at work, which comes in enormous vats ...